Our lab member Ann Cloos gave a brilliant talk at the school opening ceremony, shared her compelling journey to China and her reasons for choosing our university, highlighting the unique opportunities and collaborative spirit that drew her here.
Exciting news! We've welcomed some new faces to our lab team. Take a moment to visit our website, learn more about them, and help us give them a warm welcome.
From hibernation to neurodegeneration: how a cold-resistance protein is paving the way to dementia treatments
We show that HNRNPH1 mediates RBM3 cold-dependent exon skipping via its thermosensitive interaction with a G-rich motif within the poison exon. Our study provides novel mechanistic insights into the regulation of RBM3 and provides further targets for neuroprotective therapeutic strategies.
In this review, we examine the link between local protein synthesis and key axonal processes, and the implicated pathophysiological consequences of dysregulated local protein synthesis.